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Clinical trials for Viral Tropism

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    25 result(s) found for: Viral Tropism. Displaying page 1 of 2.
    1  2  Next»
    EudraCT Number: 2011-000799-32 Sponsor Protocol Number: PROTEST Start Date*: 2011-06-08
    Sponsor Name:Fundació Lluita contra la SIDA
    Full Title: Use of genotypic HIV-1 tropism testing in proviral DNA to guide CCR5 antagonist treatment in subjects with undetectable HIV-1 viremia
    Medical condition: Human immunodeficiency virus (HIV) infection.
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021881 - Infections and infestations 10008922 Chronic infection with HIV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2010-021785-30 Sponsor Protocol Number: A4001095 Start Date*: 2011-12-07
    Sponsor Name:ViiV Healthcare UK Limited
    Full Title: A MULTICENTER, RANDOMIZED, DOUBLE BLIND, COMPARATIVE TRIAL OF MARAVIROC + DARUNAVIR/RITONAVIR VERSUS EMTRICITABINE/TENOFOVIR + DARUNAVIR/RITONAVIR FOR THE TREATMENT OF ANTIRETROVIRAL NAÏVE HIV INFE...
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004862 10068341 HIV-1 infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) HU (Completed) SE (Prematurely Ended) FI (Prematurely Ended) BE (Prematurely Ended) ES (Prematurely Ended) GB (Prematurely Ended) AT (Completed) DK (Prematurely Ended) NL (Completed) PT (Prematurely Ended) PL (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-022293-14 Sponsor Protocol Number: ANRS146OPTIMAL Start Date*: 2012-08-22
    Sponsor Name:Inserm-ANRS
    Full Title: Optimized Phase III Trial of Immuno-stimulation with Maraviroc, a CCR5 antagonist, combined with Anti Retroviral Therapy (cART) in advanced, Late diagnosed HIV-1 infected patients with an AIDS-defi...
    Medical condition: HIV infection
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed) IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-011538-93 Sponsor Protocol Number: Maraviroc –switch Start Date*: 2010-06-07
    Sponsor Name:Imperial College London
    Full Title: A prospective, randomised study to access safety, changes in platelet reactivity, plasma cardiac biomarkers and metabolic parameters over 48 weeks in HIV-1 infected subjects undergoing a switch in...
    Medical condition: HIV
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: IE (Completed) GB (Completed)
    Trial results: View results
    EudraCT Number: 2005-001246-16 Sponsor Protocol Number: CCR104458 Start Date*: 2005-08-16
    Sponsor Name:GlaxoSmithKline Research and Development
    Full Title: A Phase III, randomized, double-blind, placebo-controlled, multicenter, parallel group study to compare the efficacy and safety of GW873140 400mg BID in combination with a ritonavir-containing opti...
    Medical condition: Treatment of HIV-1 infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: HU (Completed) IE (Completed) DK (Prematurely Ended) GB (Completed) AT (Completed) DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2005-001247-39 Sponsor Protocol Number: CCR104456 Start Date*: 2005-08-16
    Sponsor Name:GlaxoSmithKline Research and Development Ltd
    Full Title: A Phase III, randomised, double-blind, placebo-controlled, multicentre, parallel group study to compare the efficacy and safety of GW873140 400mg BID in combination with a ritonavir-containing opti...
    Medical condition: Treatment of HIV-1 infections
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: HU (Completed) DE (Completed) IE (Completed) DK (Prematurely Ended) GB (Prematurely Ended) AT (Completed)
    Trial results: View results
    EudraCT Number: 2012-003501-10 Sponsor Protocol Number: 3883 Start Date*: 2013-04-24
    Sponsor Name:Vall d'Hebron Institut de Recerca (VHIR)
    Full Title: Efficacy of dual antiretroviral treatment with maraviroc plus ritonavir-boosted darunavir in early rescue therapy in patients with HIV-1 infection: pilot, multicenter, randomized, controlled and op...
    Medical condition: Adult patients with HIV-1 infection that present virologic failure to first-line antiretroviral treatment.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10020161 HIV infection PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2004-003865-33 Sponsor Protocol Number: CCR100136 Start Date*: 2005-02-03
    Sponsor Name:GlaxoSmithKline Research & Development Ltd
    Full Title: A Phase IIb, 96 week, randomized, open-label, multicenter, parallel group, repeat dose study to evaluate the safety, tolerability, pharmacokinetics and antiviral effect of different doses and regim...
    Medical condition: Treatment of HIV-1 infection
    Disease:
    Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended) IT (Prematurely Ended) DE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2014-004692-22 Sponsor Protocol Number: NA Start Date*: 2015-11-19
    Sponsor Name:University of Torino
    Full Title: MARAT Study “Pharmacokinetics of MARaviroc and boosted ATazanavir dual regimen in stable HIV-infected patients”
    Medical condition: HIV infection
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2014-002134-31 Sponsor Protocol Number: HLS14/01 Start Date*: 2015-07-22
    Sponsor Name:Ospedale L. Sacco - Azienda Ospedaliera-Polo Universitario
    Full Title: Evalutation of maraviroc therapy in PI-treated HIV+ patients at intermediate-low risk for cardiovascular diseases: a phase IV, randomized, open study
    Medical condition: HIV-1 infection.
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018709-12 Sponsor Protocol Number: OSCAR Start Date*: 2010-09-23
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: Optimizing Susceptibility to CCR5 Antagonist Response
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008922 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2009-011868-11 Sponsor Protocol Number: MARAVI-SWITCH Start Date*: 2009-07-30
    Sponsor Name:Lluita contra la Sida Foundation
    Full Title: ENSAYO CLÍNICO PILOTO PARA EVALUAR LA SEGURIDAD Y EFICACIA DE CAMBIAR EL ITINAN O EL IP A MARAVIROC EN PACIENTES INFECTADOS POR EL VIH-1 CON CARGA VIRAL INDETECTABLE Y DISLIPEMIA ASOCIADA A LOS ANT...
    Medical condition: HIV Infection
    Disease: Version SOC Term Classification Code Term Level
    9.1 10008919 Chronic HIV infection LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2005-001057-21 Sponsor Protocol Number: PO3672 Start Date*: 2005-12-16
    Sponsor Name:Schering-Plough Research Insititute, a division of Schering Corporation
    Full Title: Vicriviroc in Combination Treatment with Optimized ART Regimen in Experienced Subjects (VICTOR-E1)
    Medical condition: HIV infection (R5-tropism only) with previous therapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10200172 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) PT (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-021651-79 Sponsor Protocol Number: SHORT-STOP-MVC Start Date*: 2011-03-22
    Sponsor Name:FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR
    Full Title: Studio degli effetti immuno-virologici dell’interruzione di Maraviroc nei pazienti che stanno fallendo un regime contenente Maraviroc
    Medical condition: patients affected by HIV in stable treatment with Maraviroc from at least 6 months
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10008922 Chronic infection with HIV LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-003614-14 Sponsor Protocol Number: RAINBOW Start Date*: 2019-12-16
    Sponsor Name:ISTITUTO NAZIONALE PER LE MALATTIE INFETTIVE "LAZZARO SPALLANZANI"
    Full Title: Feasibility, efficacy and safety of rapid (within 7 days from HIV diagnosis) antiretroviral initiation strategy based on bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) in HIV-infected na...
    Medical condition: HIV infection
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10020441 Human immunodeficiency virus infection, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-000198-21 Sponsor Protocol Number: NUKE-OUT Start Date*: 2012-04-26
    Sponsor Name:Fundació Lluita contra la SIDA
    Full Title: A multicenter randomised opened study to assess the efficacy and safety of the withdrawal of nucleos/tide analogues in HIV-1-infected subjects with complete or intermediate resistance to these anal...
    Medical condition: Infection with human immunodeficiency virus (HIV).
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10008919 Chronic HIV infection LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2017-000554-19 Sponsor Protocol Number: P25-INACTION Start Date*: 2017-10-12
    Sponsor Name:OSPEDALE SAN RAFFAELE
    Full Title: Implication for strategies of long term control of viral replication in patient with primary HIV infection (PHI) treated with multitarget antiviral therapy (MT-ART)
    Medical condition: subject whith PHI never treated
    Disease: Version SOC Term Classification Code Term Level
    20.1 10021881 - Infections and infestations 10000807 Acute HIV infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-023316-13 Sponsor Protocol Number: 1384/10 Start Date*: 2011-05-23
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Randomized multicenter study on security and efficacy of therapeutic switch to maraviroc + darunavir/ritonavir once daily in patients who are in triple antiretroviral regimen with three drugs belo...
    Medical condition: Infection of HIV
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020161 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-003866-13 Sponsor Protocol Number: CCR102881 Start Date*: 2005-02-24
    Sponsor Name:GlaxoSmithKline Research & Development Limited
    Full Title: A phase IIb, 96 week, randomised, partially,double-blinded,multicentre,parallel group, repeat dose study to evaluate the safety, tolerability, pharmacokinetics and antiviral effect of GW873140 in c...
    Medical condition: Treatment of HIV-1 infections
    Disease:
    Population Age: Adolescents, Adults Gender: Male, Female
    Trial protocol: DE (Completed) IT (Prematurely Ended) GB (Prematurely Ended) BE (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2009-016480-11 Sponsor Protocol Number: 2009HD/01 Start Date*: 2009-12-28
    Sponsor Name:P Pierre Dellamonica
    Full Title: “No Nuc, No Boost” : A phase 2 pilot study of simplification by Maraviroc-Raltegravir following 6 months of treatment with Maraviroc-Raltegravir-Tenofovir-Emtricitabine in naive patients infected b...
    Medical condition: HIV naïve patients, CCR5 tropism, with CD4 > 200/mm3 and HIV RNA < 100 000 copy/ml.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10020192 HIV-1 LLT
    Population Age: Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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